I'm still not ready to work on a graphic novel project but I'm getting there and it is definitely starting to look more feasible. I've gotten the hang of the compositor, which I mostly use so that I can have my linework and inking render layers done separately from coloring/fill layers.
Here's a great resource: a Blender ink shader. Download the .blend file and stick whatever subject you want in there for instantly great results. Here are some experiments I've been doing with this and the compositor.